Fig 1: PRR11 is a direct target of miR-204-5p in BC: (a) Venn plot for screening target mRNA; (b) results of Pearson correlation analysis; (c) violin plot of PRR11 level in TCGA (blue for normal and yellow for tumor); (d) survival analysis on PRR11 levels and survival; (e) outcomes of GSEA; (f) potential binding area between 2 genes; (g) the binding between 2 genes; (h) PRR11 levels in differing cells; (i, j) the results of qRT-PCR and western blot (* means p < 0.05).
Fig 2: miR-204-5p induces cell cycle arrest and hinders cancer cell functions via PRR11 inhibition: (a) expression of miR-204-5p and PRR11 mRNA in BC cells; (b) protein level of PRR11 was assessed by western blot; (c) cell activity of transfected cells; (d) migratory ability of transfected BC cells (×100) by the Transwell assay; (e) invasive ability of transfected BC cells (×100) by the Transwell assay; (f) cell proportion in each cell cycle phase (* means p < 0.05).
Supplier Page from Abcam for Anti-PRR11 antibody